Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates

Benzotriazole and microwave mediated syntheses led to a new set of hybrid conjugates of pyrazinoic acid with isoniazid via amino acid linkers in excellent yields with retention of chirality. Microbiological screening of the synthesized conjugates revealed an exceptionally high activity against some...

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Detalles Bibliográficos
Autores principales: Panda, Siva S., Girgis, Adel S., Mishra, Bibhuti B., Elagawany, Mohamed, Devarapalli, Venkatasai, Littlefield, William F., Samir, Ahmed, Fayad, Walid, Fawzy, Nehmedo G., Srour, Aladdin M., Bokhtia, Riham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065575/
https://www.ncbi.nlm.nih.gov/pubmed/35514723
http://dx.doi.org/10.1039/c9ra03380g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065575/
https://www.ncbi.nlm.nih.gov/pubmed/35514723
http://dx.doi.org/10.1039/c9ra03380g

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