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Synthesis and biological evaluation of an epidermal growth factor receptor-targeted peptide-conjugated phthalocyanine-based photosensitiser

A peptide-conjugated zinc(ii) phthalocyanine containing the epidermal growth factor receptor-targeted heptapeptide QRHKPRE has been prepared. The conjugate labelled as ZnPc-QRH* can selectively bind to the cell membrane of HT29 human colorectal adenocarcinoma cells in 10 min followed by internalisat...

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Detalles Bibliográficos
Autores principales: Xue, Evelyn Y., Wong, Roy C. H., Wong, Clarence T. T., Fong, Wing-Ping, Ng, Dennis K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065697/
https://www.ncbi.nlm.nih.gov/pubmed/35515550
http://dx.doi.org/10.1039/c9ra03911b