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Synthesis and biological evaluation of an epidermal growth factor receptor-targeted peptide-conjugated phthalocyanine-based photosensitiser
A peptide-conjugated zinc(ii) phthalocyanine containing the epidermal growth factor receptor-targeted heptapeptide QRHKPRE has been prepared. The conjugate labelled as ZnPc-QRH* can selectively bind to the cell membrane of HT29 human colorectal adenocarcinoma cells in 10 min followed by internalisat...
Autores principales: | Xue, Evelyn Y., Wong, Roy C. H., Wong, Clarence T. T., Fong, Wing-Ping, Ng, Dennis K. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065697/ https://www.ncbi.nlm.nih.gov/pubmed/35515550 http://dx.doi.org/10.1039/c9ra03911b |
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