pH/redox sensitive nanoparticles with platinum(iv) prodrugs and doxorubicin enhance chemotherapy in ovarian cancer

pH/redox sensitive, dual drug loaded nanoparticles were prepared from poly(ethylene glycol)-block-poly(l-lysine) (PEG-b-PLL) for improving cancer therapy. Platinum(iv) and cis-aconitic anhydride-doxorubicin (CAD) were anchored to lysine residual amine groups of PLL to form polymer prodrug conjugates...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Guyu, Zhu, Yimin, Wang, Yushu, Wei, Dengshuai, Wu, Yixin, Zheng, Liuchun, Bai, Huimin, Xiao, Haihua, Zhang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065746/
https://www.ncbi.nlm.nih.gov/pubmed/35515556
http://dx.doi.org/10.1039/c9ra04034j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065746/
https://www.ncbi.nlm.nih.gov/pubmed/35515556
http://dx.doi.org/10.1039/c9ra04034j

Ejemplares similares