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pH/redox sensitive nanoparticles with platinum(iv) prodrugs and doxorubicin enhance chemotherapy in ovarian cancer

pH/redox sensitive, dual drug loaded nanoparticles were prepared from poly(ethylene glycol)-block-poly(l-lysine) (PEG-b-PLL) for improving cancer therapy. Platinum(iv) and cis-aconitic anhydride-doxorubicin (CAD) were anchored to lysine residual amine groups of PLL to form polymer prodrug conjugates...

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Detalles Bibliográficos
Autores principales:	Zhang, Guyu, Zhu, Yimin, Wang, Yushu, Wei, Dengshuai, Wu, Yixin, Zheng, Liuchun, Bai, Huimin, Xiao, Haihua, Zhang, Zhenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065746/ https://www.ncbi.nlm.nih.gov/pubmed/35515556 http://dx.doi.org/10.1039/c9ra04034j

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