Regioselective microwave synthesis and derivatization of 1,5-diaryl-3-amino-1,2,4-triazoles and a study of their cholinesterase inhibition properties

Herein we describe the development of an efficient one-pot regioselective synthesis protocol to obtain N-protected or N-deprotected 1,5-diaryl-3-amino-1,2,4-triazoles from N-acyl-N-Boc-carbamidothioates. This improved protocol using microwave irradiation and low reaction times (up to 1 h) furnished...

Descripción completa

Detalles Bibliográficos
Autores principales: Santos, Sabrina Neves, Alves de Souza, Gabriela, Pereira, Thiago Moreira, Franco, Daiana Portella, de Nigris Del Cistia, Catarina, Sant'Anna, Carlos Mauricio R., Lacerda, Renata Barbosa, Kümmerle, Arthur Eugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065794/
https://www.ncbi.nlm.nih.gov/pubmed/35514684
http://dx.doi.org/10.1039/c9ra04105b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065794/
https://www.ncbi.nlm.nih.gov/pubmed/35514684
http://dx.doi.org/10.1039/c9ra04105b

Ejemplares similares