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Regioselective microwave synthesis and derivatization of 1,5-diaryl-3-amino-1,2,4-triazoles and a study of their cholinesterase inhibition properties

Herein we describe the development of an efficient one-pot regioselective synthesis protocol to obtain N-protected or N-deprotected 1,5-diaryl-3-amino-1,2,4-triazoles from N-acyl-N-Boc-carbamidothioates. This improved protocol using microwave irradiation and low reaction times (up to 1 h) furnished...

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Detalles Bibliográficos
Autores principales:	Santos, Sabrina Neves, Alves de Souza, Gabriela, Pereira, Thiago Moreira, Franco, Daiana Portella, de Nigris Del Cistia, Catarina, Sant'Anna, Carlos Mauricio R., Lacerda, Renata Barbosa, Kümmerle, Arthur Eugen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065794/ https://www.ncbi.nlm.nih.gov/pubmed/35514684 http://dx.doi.org/10.1039/c9ra04105b

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