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Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation

AIMS: Pressure overload (PO) and volume overload (VO) lead to concentric or eccentric hypertrophy. Previously, we could show that activation of signalling cascades differ in in vivo mouse models. Activation of these signal cascades could either be induced by intrinsic load sensing or neuro‐endocrine...

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Detalles Bibliográficos
Autores principales: Hartmann, Nico, Preuß, Lena, Mohamed, Belal A., Schnelle, Moritz, Renner, Andre, Hasenfuß, Gerd, Toischer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065823/
https://www.ncbi.nlm.nih.gov/pubmed/35315235
http://dx.doi.org/10.1002/ehf2.13877