Hoxa11-mediated reduction of cell migration contributes to myeloid sarcoma formation induced by cooperation of MLL/AF10 with activating KRAS mutation in a mouse transplantation model: Hoxa11 in myeloid sarcoma formation

The molecular mechanism of myeloid sarcoma (MS) formation remains nuclear. Our clinical and mouse model findings from a previous study revealed that cooperation of KMT2A (MLL) translocation (MLL-t) with activating N-/K-RAS mutations promoted MS formation in a shorter latency. To improve the understa...

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Detalles Bibliográficos
Autores principales: Fu, Jen-Fen, Wen, Chih-Jen, Yen, Tzung-Hai, Shih, Lee-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065885/
https://www.ncbi.nlm.nih.gov/pubmed/35500545
http://dx.doi.org/10.1016/j.neo.2022.100802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065885/
https://www.ncbi.nlm.nih.gov/pubmed/35500545
http://dx.doi.org/10.1016/j.neo.2022.100802

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