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A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice

BACKGROUND: Schistosomiasis is an underestimated neglected tropical disease which affects over 236.6 million people worldwide. According to the CDC, the impact of this disease is second to only malaria as the most devastating parasitic infection. Affected individuals manifest chronic pathology due t...

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Detalles Bibliográficos
Autores principales: Perera, Dilhan J., Hassan, Adam S., Liu, Sunny S., Elahi, Seyyed Mehdy, Gadoury, Christine, Weeratna, Risini D., Gilbert, Rénald, Ndao, Momar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065910/
https://www.ncbi.nlm.nih.gov/pubmed/35500538
http://dx.doi.org/10.1016/j.ebiom.2022.104036