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Mechanism of proteasome gate modulation by assembly chaperones Pba1 and Pba2
The active sites of the proteasome are housed within its central core particle (CP), a barrel-shaped chamber of four stacked heptameric rings, and access of substrates to the CP interior is mediated by gates at either axial end. These gates are constitutively closed and may be opened by the regulato...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065996/ https://www.ncbi.nlm.nih.gov/pubmed/35398095 http://dx.doi.org/10.1016/j.jbc.2022.101906 |