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A strategy for determining the equilibrium constants for heteromeric ion channels in a complex model

Ligand-gated ion channels are oligomers containing several binding sites for the ligands. However, the signal transmission from the ligand binding site to the pore has not yet been fully elucidated for any of these channels. In heteromeric channels, the situation is even more complex than in homomer...

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Detalles Bibliográficos
Autores principales: Benndorf, Klaus, Eick, Thomas, Sattler, Christian, Schmauder, Ralf, Schulz, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066054/
https://www.ncbi.nlm.nih.gov/pubmed/35486087
http://dx.doi.org/10.1085/jgp.202113041