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Human cerebral organoids reveal progenitor pathology in EML1‐linked cortical malformation

Malformations of human cortical development (MCD) can cause severe disabilities. The lack of human‐specific models hampers our understanding of the molecular underpinnings of the intricate processes leading to MCD. Here, we use cerebral organoids derived from patients and genome edited‐induced pluri...

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Detalles Bibliográficos
Autores principales: Jabali, Ammar, Hoffrichter, Anne, Uzquiano, Ana, Marsoner, Fabio, Wilkens, Ruven, Siekmann, Marco, Bohl, Bettina, Rossetti, Andrea C, Horschitz, Sandra, Koch, Philipp, Francis, Fiona, Ladewig, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066063/
https://www.ncbi.nlm.nih.gov/pubmed/35289477
http://dx.doi.org/10.15252/embr.202154027