LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction

LincRNA‐EPS is an important regulator in inflammation. However, the role of lincRNA‐EPS in the host response against viral infection is unexplored. Here, we show that lincRNA‐EPS is downregulated in macrophages infected with different viruses including VSV, SeV, and HSV‐1. Overexpression of lincRNA‐...

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Detalles Bibliográficos
Autores principales: Zhu, Jingfei, Chen, Shengchuan, Sun, Li‐Qiong, Liu, Siying, Bai, Xue, Li, Dapei, Zhang, Fan, Qiao, Zigang, Li, Liang, Yao, Haiping, Xia, Yu, Xu, Ping, Jiang, Xiaohui, Chen, Zhengrong, Yan, Yongdong, Ma, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066075/
https://www.ncbi.nlm.nih.gov/pubmed/35312140
http://dx.doi.org/10.15252/embr.202153937