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Post-translational Modification in Control of SIRT1 Stability during DNA Damage Response

SIRT1 (silent mating type information regulation 2 homolog 1), a class III histone deacetylase, is known to participate in multiple steps of the DNA damage response (DDR) by deacetylating several key DDR proteins. At present, the mechanisms regulating SIRT1 protein stability upon DNA damage have yet...

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Detalles Bibliográficos
Autores principales: Ouyang, Chenxi, Lu, Guang, He, Weifeng, Bay, Boon-Huat, Shen, Han-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066097/
https://www.ncbi.nlm.nih.gov/pubmed/35541916
http://dx.doi.org/10.7150/ijbs.68587