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ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistance

Palmitoylation is essential for the classic hallmarks of cancers through regulating protein stability and protein-protein interactions. ZDHHC22, as a well-known member of palmitoyltrans-ferase family, its role has not been revealed in cancer. We found ZDHHC22 expression was significantly lower in es...

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Detalles Bibliográficos
Autores principales: Huang, Jiefeng, Li, Jie, Tang, Jun, Wu, Yushen, Dai, Fengsheng, Yi, Ziying, Wang, Yan, Li, Yunhai, Wu, Yue, Ren, Guosheng, Xiang, Tingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066102/
https://www.ncbi.nlm.nih.gov/pubmed/35541896
http://dx.doi.org/10.7150/ijbs.70544