Downregulation of MTAP promotes Tumor Growth and Metastasis by regulating ODC Activity in Breast Cancer

5'-Methylthioadenosine phosphorylase (MTAP) is a key enzyme in the methionine salvage pathway and has been reported to suppress tumorigenesis. The MTAP gene is located at 9p21, a chromosome region often deleted in breast cancer (BC). However, the clinical and biological significance of MTAP in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ying, Zhang, Tian-Tian, Gao, Lin, Tan, Ya-Nan, Li, Yu-Ting, Tan, Xiang-Yu, Huang, Tu-Xiong, Li, Hua-Hui, Bai, Feng, Zou, Chang, Pei, Xin-Hai, Tan, Bin-Bin, Fu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066107/
https://www.ncbi.nlm.nih.gov/pubmed/35541910
http://dx.doi.org/10.7150/ijbs.67149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066107/
https://www.ncbi.nlm.nih.gov/pubmed/35541910
http://dx.doi.org/10.7150/ijbs.67149

Ejemplares similares