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The sphingosine kinase inhibitor SKI-V suppresses cervical cancer cell growth

Overexpression and/or overactivation of sphingosine kinase 1/2 (SphK1/2) is important for tumorigenesis and progression of cervical cancer. The current study examined the potential activity and signaling mechanisms of SKI-V, a non-lipid small molecule SphK inhibitor, against cervical cancer cells. I...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Cheng, Long, Shi, Xin, Song, Yu, Chen, Xiao-yu, Chen, Min-bin, Yao, Jin, Zhang, Zhi-qing, Cai, Shang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066110/
https://www.ncbi.nlm.nih.gov/pubmed/35541904
http://dx.doi.org/10.7150/ijbs.71381