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Toosendanin, a novel potent vacuolar-type H(+)-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy

Macroautophagy/autophagy is the process of self-digestion through the lysosomes; it disassembles unnecessary or dysfunctional long-lived proteins and damaged organelles for the recycling of biomacromolecules. Unfortunately, cancer cells can hijack this mechanism to survive under metabolic stress or...

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Detalles Bibliográficos
Autores principales: Dong, Yu, Zhu, Guoyuan, Wang, Sheng-Fang, Keon, Kristine A., Rubinstein, John L., Zeng, Si-Xin, Zhang, Shuang, Chen, Qiu-Ling, Fu, Jing, Li, Min, Shen, Han-Ming, Lu, Jin-Jian, Chen, Xiu-Ping, Lu, Jia-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066121/
https://www.ncbi.nlm.nih.gov/pubmed/35541921
http://dx.doi.org/10.7150/ijbs.71041