Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

New phenylaminopyrimidine (PAP) derivatives have been designed and synthesised as potential tyrosine kinase inhibitors for the treatment of cancer. The synthesized compounds share a general structure and vary in the substitution pattern at position-2 of the pyridine ring. Several derivatives have de...

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Detalles Bibliográficos
Autores principales: Henidi, Hanan A., Al-Abd, Ahmed M., Al-Abbasi, Fahad A., BinMahfouz, Hawazen A., El-Deeb, Ibrahim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066187/
https://www.ncbi.nlm.nih.gov/pubmed/35521305
http://dx.doi.org/10.1039/c9ra03359a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066187/
https://www.ncbi.nlm.nih.gov/pubmed/35521305
http://dx.doi.org/10.1039/c9ra03359a

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