EGLN1 induces tumorigenesis and radioresistance in nasopharyngeal carcinoma by promoting ubiquitination of p53 in a hydroxylase-dependent manner

Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) is a proline hydroxylase mediating degradation of hypoxia-inducible factor α (HIFα) through the ubiquitination system. Studies have indicated an essential role for EGLN1 in angiogenesis and tumorigenesis. However, there is no consensus on the regulatio...

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Detalles Bibliográficos
Autores principales: Sun, Lu, Wu, Cheng, Ming, Jun, Guo, Ergang, Zhang, Wei, Li, Lingling, Hu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066203/
https://www.ncbi.nlm.nih.gov/pubmed/35517429
http://dx.doi.org/10.7150/jca.66080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066203/
https://www.ncbi.nlm.nih.gov/pubmed/35517429
http://dx.doi.org/10.7150/jca.66080

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