Discovery of Cobimetinib as a novel A-FABP inhibitor using machine learning and molecular docking-based virtual screening

Adipocyte fatty acid-binding protein (A-FABP, also called FABP4, aP2) is an adipokine identified as a critical regulator of metabolic function due to its dual functions of fatty acid transport and pro-inflammation. Because of the high therapeutic potential of A-FABP inhibition for the treatment of m...

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Detalles Bibliográficos
Autores principales: Yang, Shilun, Li, Simeng, Chang, Junlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066360/
https://www.ncbi.nlm.nih.gov/pubmed/35520131
http://dx.doi.org/10.1039/d2ra01057g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066360/
https://www.ncbi.nlm.nih.gov/pubmed/35520131
http://dx.doi.org/10.1039/d2ra01057g

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