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Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells

BACKGROUND: Gastric cancer (GC) is one of the most common cancer worldwide. We analyzed the expression of m(6)A regulatory genes in GC cohorts and revealed that YTHDF1 was uniquely upregulated in GC as compared with adjacent normal tissues. In this study, we analyzed the role of YTHDF1 in GC cells a...

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Detalles Bibliográficos
Autores principales: Bai, Xiaowu, Wong, Chi Chun, Pan, Yasi, Chen, Huarong, Liu, Weixin, Zhai, Jianning, Kang, Wei, Shi, Yu, Yamamoto, Masami, Tsukamoto, Tetsuya, Nomura, Sachiyo, Chiu, Philip, Yu, Jun, Kwok-wai Ng, Enders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066370/
https://www.ncbi.nlm.nih.gov/pubmed/35193930
http://dx.doi.org/10.1136/jitc-2021-003663