Cargando…
Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells
BACKGROUND: Gastric cancer (GC) is one of the most common cancer worldwide. We analyzed the expression of m(6)A regulatory genes in GC cohorts and revealed that YTHDF1 was uniquely upregulated in GC as compared with adjacent normal tissues. In this study, we analyzed the role of YTHDF1 in GC cells a...
Autores principales: | Bai, Xiaowu, Wong, Chi Chun, Pan, Yasi, Chen, Huarong, Liu, Weixin, Zhai, Jianning, Kang, Wei, Shi, Yu, Yamamoto, Masami, Tsukamoto, Tetsuya, Nomura, Sachiyo, Chiu, Philip, Yu, Jun, Kwok-wai Ng, Enders |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066370/ https://www.ncbi.nlm.nih.gov/pubmed/35193930 http://dx.doi.org/10.1136/jitc-2021-003663 |
Ejemplares similares
-
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity
por: Wang, Zining, et al.
Publicado: (2021) -
TFAM deficiency in dendritic cells leads to mitochondrial dysfunction and enhanced antitumor immunity through cGAS-STING pathway
por: Lu, Tianqi, et al.
Publicado: (2023) -
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity
por: Fernandez-Rodriguez, Laura, et al.
Publicado: (2023) -
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
por: Cueto, Francisco J, et al.
Publicado: (2021) -
Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein
por: Torres, Nicolas, et al.
Publicado: (2020)