Drug Conjugation via Maleimide–Thiol Chemistry Does Not Affect Targeting Properties of Cysteine-Containing Anti-FGFR1 Peptibodies

[Image: see text] With a wide range of available cytotoxic therapeutics, the main focus of current cancer research is to deliver them specifically to the cancer cells, minimizing toxicity against healthy tissues. Targeted therapy utilizes different carriers for cytotoxic drugs, combining a targeting...

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Detalles Bibliográficos
Autores principales: Jendryczko, Karolina, Rzeszotko, Jakub, Krzyscik, Mateusz Adam, Kocyła, Anna, Szymczyk, Jakub, Otlewski, Jacek, Szlachcic, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066409/
https://www.ncbi.nlm.nih.gov/pubmed/35389227
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066409/
https://www.ncbi.nlm.nih.gov/pubmed/35389227
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00946

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