The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Paget's disease of bone (PDB) is characterized by focal increases in bone remodelling. Genome-wide association studies identified a susceptibility locus for PDB tagged by rs5742915, which is located within the PML gene. Here, we have assessed the candidacy of PML as the predisposing gene for PD...

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Detalles Bibliográficos
Autores principales: Wani, Sachin, Daroszewska, Anna, Salter, Donald M., van ‘t Hof, Rob J., Ralston, Stuart H., Albagha, Omar M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066519/
https://www.ncbi.nlm.nih.gov/pubmed/35229101
http://dx.doi.org/10.1242/dmm.049318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066519/
https://www.ncbi.nlm.nih.gov/pubmed/35229101
http://dx.doi.org/10.1242/dmm.049318

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