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Histological, functional and transcriptomic alterations in the juvenile hippocampus in a mouse model of thyroid hormone resistance

BACKGROUND: Proper thyroid hormone signaling via the TRα1 nuclear receptor is required for normal neurodevelopmental processes. The specific downstream mechanisms mediated by TRα1 that impact brain development remain to be investigated. METHODS: In this study, the structure, function and transcripto...

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Detalles Bibliográficos
Autores principales: Fang, Yingxin, Dang, Pingping, Liang, Yue, Zhao, Defa, Wang, Ranran, Xi, Yue, Zhang, Dan, Wang, Wei, Shan, Zhongyan, Teng, Weiping, Teng, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066571/
https://www.ncbi.nlm.nih.gov/pubmed/35262510
http://dx.doi.org/10.1530/ETJ-21-0097