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Txnip deficiency promotes β-cell proliferation in the HFD-induced obesity mouse model

Elucidating the mechanisms of regulation of β-cell proliferation is key to understanding the pathogenesis of diabetes mellitus. Txnip is a tumor suppressor that is upregulated in diabetes and plays an important role in the regulation of insulin sensitivity; however, its potential effect on pancreati...

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Detalles Bibliográficos
Autores principales: Lei, Zhandong, Chen, Yunfei, Wang, Jin, Zhang, Yan, Shi, Wenjuan, Wang, Xuejiao, Xing, Dehai, Li, Dongxue, Jiao, Xiangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066588/
https://www.ncbi.nlm.nih.gov/pubmed/35294398
http://dx.doi.org/10.1530/EC-21-0641