Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology

Based on the epidemiological link between periodontitis and rheumatoid arthritis (RA), and the unique feature of the periodontal bacterium Porphyromonas gingivalis to citrullinate proteins, it has been suggested that production of anti-citrullinated protein antibodies (ACPA), which are present in a...

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Detalles Bibliográficos
Autores principales: Sherina, Natalia, de Vries, Charlotte, Kharlamova, Nastya, Sippl, Natalie, Jiang, Xia, Brynedal, Boel, Kindstedt, Elin, Hansson, Monika, Mathsson-Alm, Linda, Israelsson, Lena, Stålesen, Ragnhild, Saevarsdottir, Saedis, Holmdahl, Rikard, Hensvold, Aase, Johannsen, Gunnar, Eriksson, Kaja, Sallusto, Federica, Catrina, Anca I., Rönnelid, Johan, Grönwall, Caroline, Yucel-Lindberg, Tülay, Alfredsson, Lars, Klareskog, Lars, Piccoli, Luca, Malmström, Vivianne, Amara, Khaled, Lundberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066602/
https://www.ncbi.nlm.nih.gov/pubmed/35514991
http://dx.doi.org/10.3389/fimmu.2022.804822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066602/
https://www.ncbi.nlm.nih.gov/pubmed/35514991
http://dx.doi.org/10.3389/fimmu.2022.804822

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