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A titanium tetrachloride-based effective methodology for the synthesis of dipeptides

A series of dipeptide systems have been easily achieved through a TiCl(4)-assisted condensation reaction. The reaction of N-protected amino acids with amino acid methyl esters in pyridine and in the presence of TiCl(4) furnished the corresponding dipeptides with high yields and diastereoselectivity....

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Detalles Bibliográficos
Autores principales: Comandè, Alessandra, Greco, Marianna, Belsito, Emilia Lucia, Liguori, Angelo, Leggio, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066614/
https://www.ncbi.nlm.nih.gov/pubmed/35518841
http://dx.doi.org/10.1039/c9ra04058g