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Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma

BACKGROUND: Ferroptosis is an iron dependent cell death closely associated with p53 signaling pathway and is aberrantly regulated in glioblastoma (GBM), yet the underlying mechanism needs more exploration. Identifying new factors which regulate p53 and ferroptosis in GBM is essential for treatment....

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Detalles Bibliográficos
Autores principales: Sun, Qian, Xu, Yang, Yuan, Fan’en, Qi, Yangzhi, Wang, Yixuan, Chen, Qianxue, Liu, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066768/
https://www.ncbi.nlm.nih.gov/pubmed/35505371
http://dx.doi.org/10.1186/s13578-022-00791-w