Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases

BACKGROUND: The interferon response can influence the primary and metastatic activity of breast cancers and can interact with checkpoint immunotherapy to modulate its effects. Using N-ethyl-N-nitrosourea mutagenesis, we found a mouse with an activating mutation in oligoadenylate synthetase 2 (Oas2),...

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Detalles Bibliográficos
Autores principales: Ho, Wing-Hong Jonathan, Law, Andrew M. K., Masle-Farquhar, Etienne, Castillo, Lesley E., Mawson, Amanda, O’Bryan, Moira K., Goodnow, Christopher C., Gallego-Ortega, David, Oakes, Samantha R., Ormandy, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066770/
https://www.ncbi.nlm.nih.gov/pubmed/35505346
http://dx.doi.org/10.1186/s13058-022-01525-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066770/
https://www.ncbi.nlm.nih.gov/pubmed/35505346
http://dx.doi.org/10.1186/s13058-022-01525-z

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