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Enhanced DNA and RNA pathogen detection via metagenomic sequencing in patients with pneumonia

BACKGROUND: Metagenomic next-generation sequencing (mNGS) is an important supplement to conventional tests for pathogen detections of pneumonia. However, mNGS pipelines were limited by irregularities, high proportion of host nucleic acids, and lack of RNA virus detection. Thus, a regulated pipeline...

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Detalles Bibliográficos
Autores principales: He, Yukun, Fang, Kechi, Shi, Xing, Yang, Donghong, Zhao, Lili, Yu, Wenyi, Zheng, Yali, Xu, Yu, Ma, Xinqian, Chen, Li, Xie, Yu, Yu, Yan, Wang, Jing, Gao, Zhancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066823/
https://www.ncbi.nlm.nih.gov/pubmed/35509078
http://dx.doi.org/10.1186/s12967-022-03397-5