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Enhanced DNA and RNA pathogen detection via metagenomic sequencing in patients with pneumonia
BACKGROUND: Metagenomic next-generation sequencing (mNGS) is an important supplement to conventional tests for pathogen detections of pneumonia. However, mNGS pipelines were limited by irregularities, high proportion of host nucleic acids, and lack of RNA virus detection. Thus, a regulated pipeline...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066823/ https://www.ncbi.nlm.nih.gov/pubmed/35509078 http://dx.doi.org/10.1186/s12967-022-03397-5 |