Two statins and cromolyn as possible drugs against the cytotoxicity of Aβ(31–35) and Aβ(25–35) peptides: a comparative study by advanced computer simulation methods

In this work, possible effective mechanisms of cromolyn, atorvastatin and lovastatin on the cytotoxicity of Aβ(31–35) and Aβ(25–35) peptides were investigated by classical molecular dynamics and well-tempered metadynamics simulations. The results demonstrate that all the drugs affect the behavior of...

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Detalles Bibliográficos
Autores principales: Blomgren, Fredrik, Rodin, Alexander, Chrobak, Wojciech, Pacut, Dawid Wojciech, Swenson, Jan, Ermilova, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066867/
https://www.ncbi.nlm.nih.gov/pubmed/35520132
http://dx.doi.org/10.1039/d2ra01963a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066867/
https://www.ncbi.nlm.nih.gov/pubmed/35520132
http://dx.doi.org/10.1039/d2ra01963a

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