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Single-cell N(6)-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapy
BACKGROUND: N6-methyladenosine (m(6)A) RNA methylation plays a critical role in key genetic events for various cancers; yet, how m(6)A functions within the tumor microenvironment (TME) remains to be elucidated. METHODS: A total of 65,362 single cells from single-cell RNA-seq data derived from 33 CRC...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066909/ https://www.ncbi.nlm.nih.gov/pubmed/35509079 http://dx.doi.org/10.1186/s12967-022-03395-7 |