Single-cell N(6)-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapy

BACKGROUND: N6-methyladenosine (m(6)A) RNA methylation plays a critical role in key genetic events for various cancers; yet, how m(6)A functions within the tumor microenvironment (TME) remains to be elucidated. METHODS: A total of 65,362 single cells from single-cell RNA-seq data derived from 33 CRC...

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Detalles Bibliográficos
Autores principales: Gao, Yuzhen, Wang, Hao, Chen, Shipeng, An, Rui, Chu, Yadong, Li, Guoli, Wang, Yanzhong, Xie, Xinyou, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066909/
https://www.ncbi.nlm.nih.gov/pubmed/35509079
http://dx.doi.org/10.1186/s12967-022-03395-7

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