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EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes

BACKGROUND: The conversion of astrocytes activated by nerve injuries to oligodendrocytes is not only beneficial to axonal remyelination, but also helpful for reversal of glial scar. Recent studies have shown that pathological niche promoted the Sox10-mediated astrocytic transdifferentiation to oligo...

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Detalles Bibliográficos
Autores principales: Liu, Xinyu, Li, Conghui, Li, Jiao, Xie, Lesi, Hong, Zeng, Zheng, Kang, Zhao, Xiaofeng, Yang, Aifen, Xu, Xiaofeng, Tao, Huaping, Qiu, Mengsheng, Yang, Junlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066914/
https://www.ncbi.nlm.nih.gov/pubmed/35508991
http://dx.doi.org/10.1186/s10020-022-00478-5