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A novel chronic dural port platform for continuous collection of cerebrospinal fluid and intrathecal drug delivery in free-moving mice

BACKGROUND: Cerebrospinal fluid (CSF) provides a close representation of pathophysiological changes occurring in the central nervous system (CNS); therefore, it has been employed in pathogenesis research and biomarker development for CNS disorders. CSF obtained from valid mouse models relevant to CN...

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Detalles Bibliográficos
Autores principales: Nakajima, Tsuneo, Takeda, Shuko, Ito, Yuki, Oyama, Akane, Takami, Yoichi, Takeya, Yasushi, Yamamoto, Koichi, Sugimoto, Ken, Shimizu, Hideo, Shimamura, Munehisa, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066940/
https://www.ncbi.nlm.nih.gov/pubmed/35505336
http://dx.doi.org/10.1186/s12987-022-00331-1