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Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

BACKGROUND: The activation of immune response driven by the eggs of Schistosoma japonicum and the subsequent secretions is the culprit behind granulomatous inflammation and liver fibrosis. Evidence suggests that PKCλ/ι participates in a variety of physiological and pathological processes, including...

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Detalles Bibliográficos
Autores principales: Mei, Congjin, Yang, Yingying, Dong, Panpan, Song, Lijun, Zhou, Yonghua, Xu, Yongliang, Yu, Chuanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066985/
https://www.ncbi.nlm.nih.gov/pubmed/35505421
http://dx.doi.org/10.1186/s13071-022-05283-x