Inhibition of PIKfyve Ameliorates the Proliferation and Migration of Vascular Smooth Muscle Cells and Vascular Intima Hyperplasia By Reducing mTORC1 Activity

This study was designed to investigate the role and mechanism of PIKfyve in the proliferation and migration of vascular smooth muscle cells (VSMCs) and vascular intima hyperplasia. We first observed increased protein levels of PIKfyve, phospho (p)-S6 Ribosomal Protein (S6)(Ser235/236), p-4EBP1(Thr37...

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Detalles Bibliográficos
Autores principales: Gu, Min, Wang, Zhen, Feng, Feifei, Yang, Yongjian, Sun, Xiongshan, Yang, Dachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067083/
https://www.ncbi.nlm.nih.gov/pubmed/35275098
http://dx.doi.org/10.1097/FJC.0000000000001243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067083/
https://www.ncbi.nlm.nih.gov/pubmed/35275098
http://dx.doi.org/10.1097/FJC.0000000000001243

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