Cargando…

Isoform‐specific effects of transcription factor TCFL5 on the pluripotency‐related genes SOX2 and KLF4 in colorectal cancer development

Colorectal cancer (CRC) is a very common life‐threatening malignancy. Transcription factor‐like 5 (TCFL5) has been suggested to be involved in CRC. Here, we describe the expression of four alternative transcripts of TCFL5 and their relevance in CRC. Complete deletion of all isoforms drastically decr...

Descripción completa

Detalles Bibliográficos
Autores principales: Galán‐Martínez, Javier, Stamatakis, Konstantinos, Sánchez‐Gómez, Inés, Vázquez‐Cuesta, Silvia, Gironés, Núria, Fresno, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067154/
https://www.ncbi.nlm.nih.gov/pubmed/34623757
http://dx.doi.org/10.1002/1878-0261.13085