Cargando…

Isoform‐specific effects of transcription factor TCFL5 on the pluripotency‐related genes SOX2 and KLF4 in colorectal cancer development

Colorectal cancer (CRC) is a very common life‐threatening malignancy. Transcription factor‐like 5 (TCFL5) has been suggested to be involved in CRC. Here, we describe the expression of four alternative transcripts of TCFL5 and their relevance in CRC. Complete deletion of all isoforms drastically decr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galán‐Martínez, Javier, Stamatakis, Konstantinos, Sánchez‐Gómez, Inés, Vázquez‐Cuesta, Silvia, Gironés, Núria, Fresno, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067154/ https://www.ncbi.nlm.nih.gov/pubmed/34623757 http://dx.doi.org/10.1002/1878-0261.13085

Ejemplares similares

TCFL5 deficiency impairs the pachytene to diplotene transition during spermatogenesis in the mouse
por: Galán-Martínez, Javier, et al.
Publicado: (2022)

Grammar System of TCFL Driven by Neural Network Technology
por: Xiao, Rui, et al.
Publicado: (2022)

Retracted: Grammar System of TCFL Driven by Neural Network Technology
por: Intelligence and Neuroscience, Computational
Publicado: (2023)

The transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in mice
por: Cecchini, Katharine, et al.
Publicado: (2023)

Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4
por: Corbineau, Sébastien, et al.
Publicado: (2016)

KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
por: Bernhardt, Celine, et al.
Publicado: (2022)

Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis
por: Guo, Changcheng, et al.
Publicado: (2022)

Genome organization by Klf4 regulates transcription in pluripotent stem cells
por: Huang, David, et al.
Publicado: (2013)

A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals
por: Yu, Tiangxiong, et al.
Publicado: (2023)

AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts
por: Adamo, Luigi, et al.
Publicado: (2009)

Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications
por: Herreros-Cabello, Alfonso, et al.
Publicado: (2020)

KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control
por: Dhaliwal, Navroop K., et al.
Publicado: (2019)

Regulatory Lymphoid and Myeloid Cells Determine the Cardiac Immunopathogenesis of Trypanosoma cruzi Infection
por: Fresno, Manuel, et al.
Publicado: (2018)

Myeloid-Derived Suppressor Cells in Trypanosoma cruzi Infection
por: Fresno, Manuel, et al.
Publicado: (2021)

Gene expression of OCT4, SOX2, KLF4 and MYC (OSKM) induced pluripotent stem cells: identification for potential mechanisms
por: Cai, Yanning, et al.
Publicado: (2015)

KLF3 promotes the 8‐cell‐like transcriptional state in pluripotent stem cells
por: Hao, Jing, et al.
Publicado: (2020)

Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E(2) synthase up-regulation for colorectal cancer progression
por: Stamatakis, Konstantinos, et al.
Publicado: (2015)

Application of the Yamanaka Transcription Factors Oct4, Sox2, Klf4, and c-Myc from the Laboratory to the Clinic
por: Aguirre, Marisol, et al.
Publicado: (2023)

The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation
por: Schmidt, Ryan, et al.
Publicado: (2012)

Genome Sequence of Trypanosoma cruzi Strain Bug2148
por: Callejas-Hernández, Francisco, et al.
Publicado: (2018)

Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells
por: Verneri, Paula, et al.
Publicado: (2020)

The KLF14 Transcription Factor Regulates Glycolysis by Downregulating LDHB in Colorectal Cancer
por: Wu, Guiyang, et al.
Publicado: (2019)

Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity
por: Poveda, Cristina, et al.
Publicado: (2020)

Analysis of the Dynamics of Infiltrating CD4(+) T Cell Subsets in the Heart during Experimental Trypanosoma cruzi Infection
por: Sanoja, Cristina, et al.
Publicado: (2013)

Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014)

KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
por: Kim, Shin-Il, et al.
Publicado: (2015)

Klf5 suppresses ERK signaling in mouse pluripotent stem cells
por: Azami, Takuya, et al.
Publicado: (2018)

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency
por: Huang, Yinghua, et al.
Publicado: (2020)

Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency
por: Borisova, Evgeniia, et al.
Publicado: (2021)

KLF17 promotes human naïve pluripotency but is not required for its establishment
por: Lea, Rebecca A., et al.
Publicado: (2021)

Effects of Klf4 and c-Myc Knockdown on Pluripotency Maintenance in Porcine Induced Pluripotent Stem Cell
por: Liao, Yu-Jing, et al.
Publicado: (2018)

Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer
por: Hidalgo-Estévez, Alicia M., et al.
Publicado: (2020)

Evaluation of the Effect of Orlistatorlistat on Expression of OCT4, Nanog, SOX2, and KLF4 Genes in Colorectal Cancer SW40 Cell Line
por: Noroozi Karimabad, Mojgan, et al.
Publicado: (2021)

N-Myc Regulates Expression of Pluripotency Genes in Neuroblastoma Including lif, klf2, klf4, and lin28b
por: Cotterman, Rebecca, et al.
Publicado: (2009)

DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression
por: Jiménez-Martínez, Marta, et al.
Publicado: (2019)

KLF4 transcription factor in tumorigenesis
por: He, Zhihong, et al.
Publicado: (2023)

Sox2 modulation increases naïve pluripotency plasticity
por: Tremble, Kathryn C., et al.
Publicado: (2021)

circRNA TCFL5 Promote Esophageal Cancer Progression by Modulating M2 Macrophage Polarization via the miR-543-FMNL2 Axis
por: Lin, Chengbin, et al.
Publicado: (2022)

The Complete Mitochondrial DNA of Trypanosoma cruzi: Maxicircles and Minicircles
por: Callejas-Hernández, Francisco, et al.
Publicado: (2021)

The Dual-Specificity Phosphatase 10 (DUSP10): Its Role in Cancer, Inflammation, and Immunity
por: Jiménez-Martínez, Marta, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8vptd9nked96403s3qc7j0qgr0