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High-Resolution Digital Panorama of Multiple Structures in Whole Brain of Alzheimer's Disease Mice

Simultaneously visualizing Amyloid-β (Aβ) plaque with its surrounding brain structures at the subcellular level in the intact brain is essential for understanding the complex pathology of Alzheimer's disease, but is still rarely achieved due to the technical limitations. Combining the micro-opt...

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Detalles Bibliográficos
Autores principales: Yin, Xianzhen, Zhang, Xiaochuan, Zhang, Jingjing, Yang, Weicheng, Sun, Xian, Zhang, Haiyan, Gao, Zhaobing, Jiang, Hualiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067162/
https://www.ncbi.nlm.nih.gov/pubmed/35516801
http://dx.doi.org/10.3389/fnins.2022.870520