Molecular interaction studies on ellagic acid for its anticancer potential targeting pyruvate dehydrogenase kinase 3

Pyruvate dehydrogenase kinase 3 (PDK3) plays a central role in the cancer metabolic switch through the reversible phosphorylation of pyruvate dehydrogenase complex thereby blocking the entry of pyruvate for its catabolism into the TCA cycle, and thus it is considered as an important drug target for...

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Detalles Bibliográficos
Autores principales: Dahiya, Rashmi, Mohammad, Taj, Gupta, Preeti, Haque, Anzarul, Alajmi, Mohamed F., Hussain, Afzal, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067284/
https://www.ncbi.nlm.nih.gov/pubmed/35514501
http://dx.doi.org/10.1039/c9ra02864a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067284/
https://www.ncbi.nlm.nih.gov/pubmed/35514501
http://dx.doi.org/10.1039/c9ra02864a

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