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H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats

Six methyltransferases divide labor in establishing genomic profiles of histone H3 lysine 9 methylation (H3K9me), an epigenomic modification controlling constitutive heterochromatin, gene repression, and silencing of retroelements. Among them, SETDB1 is recruited to active chromatin domains to silen...

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Detalles Bibliográficos
Autores principales: Gualdrini, Francesco, Polletti, Sara, Simonatto, Marta, Prosperini, Elena, Pileri, Francesco, Natoli, Gioacchino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067402/
https://www.ncbi.nlm.nih.gov/pubmed/35361678
http://dx.doi.org/10.1101/gad.349282.121