Functional dissection of human mitotic genes using CRISPR–Cas9 tiling screens

The identity of human protein-coding genes is well known, yet our in-depth knowledge of their molecular functions and domain architecture remains limited by shortcomings in homology-based predictions and experimental approaches focused on whole-gene depletion. To bridge this knowledge gap, we develo...

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Detalles Bibliográficos
Autores principales: Herman, Jacob A., Arora, Sonali, Carter, Lucas, Zhu, Jun, Biggins, Sue, Paddison, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Resource/Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067404/
https://www.ncbi.nlm.nih.gov/pubmed/35483740
http://dx.doi.org/10.1101/gad.349319.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067404/
https://www.ncbi.nlm.nih.gov/pubmed/35483740
http://dx.doi.org/10.1101/gad.349319.121

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