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CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart

The nucleosome remodeling and deacetylase (NuRD) complex is one of the central chromatin remodeling complexes that mediates gene repression. NuRD is essential for numerous developmental events, including heart development. Clinical and genetic studies have provided direct evidence for the role of ch...

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Detalles Bibliográficos
Autores principales: Robbe, Zachary L., Shi, Wei, Wasson, Lauren K., Scialdone, Angel P., Wilczewski, Caralynn M., Sheng, Xinlei, Hepperla, Austin J., Akerberg, Brynn N., Pu, William T., Cristea, Ileana M., Davis, Ian J., Conlon, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067406/
https://www.ncbi.nlm.nih.gov/pubmed/35450884
http://dx.doi.org/10.1101/gad.349154.121