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CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart
The nucleosome remodeling and deacetylase (NuRD) complex is one of the central chromatin remodeling complexes that mediates gene repression. NuRD is essential for numerous developmental events, including heart development. Clinical and genetic studies have provided direct evidence for the role of ch...
Autores principales: | Robbe, Zachary L., Shi, Wei, Wasson, Lauren K., Scialdone, Angel P., Wilczewski, Caralynn M., Sheng, Xinlei, Hepperla, Austin J., Akerberg, Brynn N., Pu, William T., Cristea, Ileana M., Davis, Ian J., Conlon, Frank L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067406/ https://www.ncbi.nlm.nih.gov/pubmed/35450884 http://dx.doi.org/10.1101/gad.349154.121 |
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