In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformation

Genome organization plays a pivotal role in transcription, but how transcription factors (TFs) rewire the structure of the genome to initiate and maintain the programs that lead to oncogenic transformation remains poorly understood. Acute promyelocytic leukemia (APL) is a fatal subtype of leukemia d...

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Detalles Bibliográficos
Autores principales: Mas, Glòria, Santoro, Fabio, Blanco, Enrique, Gamarra Figueroa, Gianni Paolo, Le Dily, François, Frigè, Gianmaria, Vidal, Enrique, Mugianesi, Francesca, Ballaré, Cecilia, Gutierrez, Arantxa, Sparavier, Aleksandra, Marti-Renom, Marc A., Minucci, Saverio, Di Croce, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067408/
https://www.ncbi.nlm.nih.gov/pubmed/35450883
http://dx.doi.org/10.1101/gad.349115.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067408/
https://www.ncbi.nlm.nih.gov/pubmed/35450883
http://dx.doi.org/10.1101/gad.349115.121

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