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CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation

It has recently been shown that CFIm25, a canonical mRNA 3’ processing factor, could play a variety of physiological roles through its molecular function in the regulation of mRNA alternative polyadenylation (APA). Here, we used CRISPR/Cas9-mediated gene editing approach in human embryonic stem cell...

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Detalles Bibliográficos
Autores principales: Ran, Yi, Huang, Shanshan, Shi, Junjie, Feng, Qiumin, Deng, Yanhui, Xiang, Andy Peng, Yao, Chengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067535/
https://www.ncbi.nlm.nih.gov/pubmed/35491945
http://dx.doi.org/10.1080/15476286.2022.2071025